"BioNTech is revising plans for African Vaccine Factory Network"

" BioNTech is revising plans for African Vaccine Factory Network \r\n\r\nBioNTech SE is revising plans to build a manufacturing network of vaccine plants in three countries in Africa, just over a year after breaking ground on the first facility in Rwanda.\r\n\r\nIn a potential blow for Africa\u2019s hopes of greater vaccine self-reliance, the German biotech company is currently not moving forward with a plan for a manufacturing facility in South Africa, according to people familiar with the project, who asked not to be identified discussing confidential information. In Senegal, BioNTech is now holding discussions about developing a smaller-scale manufacturing site or possibly an R&D center.\r\n\r\nThe moves come after BioNTech shipped six containers to Kigali, Rwanda, in March. The company designed its \u2018BioNTainer\u2019 facilities as part of an ambitious program to help ensure people on the continent have equitable access to the mRNA technology that soared to prominence during the race to develop a vaccine against Covid-19.\r\n\r\nBioNTech said as recently as December that in addition to Rwanda, where construction is continuing, it expected to ship BioNTainers to Senegal and potentially South Africa as part of a push toward a \u201cdecentralized and robust end-to-end manufacturing network in Africa.\u201d\r\n\r\nIn response to questions from Bloomberg, BioNTech said its \u201cgoal of helping to democratize access to innovative medicines remains unchanged.\u201d It said work to establish commercial-scale vaccine facilities in Rwanda is under way, but it made no reference to manufacturing in South Africa. It said it\u2019s currently focused on conducting clinical trials on an mRNA-based tuberculosis shot in the country at the foot of the continent.\r\n\r\nWhen the BioNTainers landed in Rwanda, the timeline on the delivery was already longer than BioNTech initially announced when it broke ground on the Kigali site in June 2022. At that point, the drugmaker said its target was to deliver the first set of BioNTainers by the end of 2022. Manufacturing in the BioNTainers was expected to start about 12 to 18 months after their installation, BioNTech said.\r\n\r\n Local Infrastructure \r\n\r\nEach BioNTainer module is composed of six ISO-sized shipping containers, and the Rwanda site will have two modules. Though the modules are self-sufficient, they rely on local infrastructure for logistics, quality control, warehousing and cold and frozen storage, according to a presentation BioNTech made during a European Parliament visit to Mainz, Germany, last year. They would be able to produce about 50 million doses of Covid vaccine, according to the presentation.\r\n\r\nPlans for a manufacturing facility in South Africa haven\u2019t moved forward in six months, and there has been no communication with potential local partners since late March, the people familiar said.\r\n\r\nThere\u2019s no set date for the arrival of BioNTainers in Senegal, and talks with BioNTech are ongoing, said Lamine Sene, senior project manager for the vaccine manufacturing facility of the Institut Pasteur de Dakar. \u201cThe project is moving forward,\u201d Sene said. \u201cWe\u2019re not working on the same schedule as Rwanda or South Africa.\u201d\r\n\r\nRwandan government representatives didn\u2019t return a call seeking comment on Friday."

"BioNTech is revising plans for African Vaccine Factory Network"

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